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#2990 Pitfalls in Glucagon-Like Peptide-1 Receptor Imaging
Introduction: Physiological pancreatico-duodenal DOTA-Exendin-4 uptake in the Brunner’s glands of the proximal duodenum occurs in Glucagon-like peptide-1 receptor (GLP-1R) imaging and is a known potential pitfall.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Antwi K
Authors: Antwi K, Hepprich M, Reubi J, Christ E, Wild D,
Keywords: insulinoma, GLP-1R imaging,
Introduction: Benign insulinomas are the most prevalent cause of endogenous hyperinsulinaemic hypoglycaemia (EHH) in adults and due to their small size difficult to localise.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Antwi A, Heye T, Fani M, Nicolas G, Merkle E,
Keywords: Insulinoma, neuroendocrine tumor, GLP-1R imaging,
Introduction: Malignant insulinomas are extremely rare in children. Localizing metastases of insulinoma is challenging. Imaging modalities like CT and MRI show limited results. Somatostatin-receptor (SSTR) imaging (SRS) performs better. However, a subgroup of malignant insulinoma lack SSRT-2 and can, therefore, not be localized using SRS. We propose that in these cases GLP-1R imaging, using the stable GLP-1 analog exendin, could play an important role.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Boss M
Authors: Boss M, de Herder W, Hussain K, Shah P, Brom M,
Keywords: Metastatic insulinoma, GLP-1R, PET, exendin,